On the same 65.000 € gross, a worker takes home roughly CHF 20'996 more per year in Switzerland than in Germany. That gap reflects the tax structure alone — before rent, healthcare, or savings behaviour come into play.
Housing is the first multiplier. Switzerland has very high rent pressure, while Germany has moderate rent pressure. That means part of the higher take-home in Switzerland can be absorbed by rent if you land in a major city.
Healthcare and pensions go in the opposite direction. Switzerland runs a public healthcare model — Mandatory private health insurance (~CHF 350+/month) outside payroll. Germany uses a public model — Statutory health insurance (~14.6% split with employer) gives full coverage. The country with lower take-home often shifts costs that the other country leaves to your private budget.
Net-of-everything, a relocation decision should weigh basic public welfare in Switzerland against comprehensive welfare state in Germany, plus differences in pension capture, social safety nets, and city-level cost of living.